Two hundred years after Mary Shelley's novel the brilliant but mad Doctor (Thomas Kretschmann) has sustained his creature and himself over two centuries through genetic experimentation. In present-day America Detective O'Connor (Parker Posey) is investigating a series of horrific murders which leads her to the doctor and his creature. What she uncovers reveals the strange evolution the doctor and his creation undergo over the course of two centuries and the divergent paths creator and monster take in pursuing good or evil.　　在玛(mǎ)丽(lì)·雪(xuě)莱(lái)的小说(shuō)两百(bǎi)年(nián)后(hòu)，才华(huá)横(héng)溢但(dàn)疯狂(kuáng)的医生使他自(zì)己(jǐ)和他的怪物从(cóng)两个世纪前(qián)的当初的实(shí)验(yàn)一直(zhí)幸存(cún)下来(lái)如(rú)今(jīn)，美(měi)国(guó)探(tàn)员(yuán) O'Connor 在调(diào)查(chá)系(xì)列(liè)谋(móu)杀(shā)案(àn)时(shí)，被引(yǐn)向(xiàng)了(le)医生和他的怪物，并(bìng)揭(jiē)露(lù)出(chū)在长达(dá)两个多(duō)世纪的漫(màn)长岁月(yuè)中(zhōng)，医生和他作(zuò)品(pǐn)间(jiān)的奇(qí)特(tè)演(yǎn)变(biàn)和他们(men)踏上(shàng)善(shàn)与恶(è)的不(bù)同(tóng)道(dào)路。